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Showing posts from February, 2022

What are the gatekeepers of the protein factory?

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NAC the Nascent polypeptide Associated complex is a cytosolic protein complex serves as a gatekeeper in protein synthesis  which regulates the transport of protein within the cells. NAC is composed of NAC alpha and NAC beta .NAC binds reversibly to the ribosomes where it is in contact with nascent chains as they emerge from the ribosomes.   In Nascent polypeptide Associated complex is functionally versatile protein complex that is involved in protein biogenesis ,assembly and transportation and that plays a key role in maintaining protein homeostasis .In all eukaryotes NAC is composed of a heterodimer consisting of an alpha and beta subunits . The study shows the molecular function of NAC as gatekeeper, granting SRP only access for those nascent proteins whose destination is the endoplasmic reticulum.   Role of the Nascent polypeptide Associated complex:   NAC plays a key role in the attachment of cytosolic ribosomes to mitochondria and promotes translational distribution of proteins

What are the reasons of hormonal imbalance?

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    Hormones are the chemical messengers of body which travel through the bloodstream instructing tissues and organs. Hormones take part in different metabolism and therefore affect many different processes in the body. Hormones affect sexual function, reproduction, metabolism .Hormones are very powerful and can have serious effect on body. Causes of Hormonal imbalance: Thyroid issue: An overactive or underactive thyroid causes imbalances in the levels of thyroid hormones in your body.     Stress: Stress is dangerous for your body because stress causes your body to produce cortisol .Long term stress make your body to produce too much level of cortisol and this effects the hormonal level.   Birth control pills : Some types of birth control pills have some hormones in them which affect the hormones in your body and they can effect your periods and cause heavy bleeding, weight gain and digestive problems. Eating disorder: Eating disorder can affect your h

What do we need to know about irritable bowel syndrome?

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  Irritable bowel syndrome is a disease that include repeated pain in your abdomen and changes in your bowel movement which may be diarrhea, constipation. The signs and symptoms of IBS are given below; 1.   Abdominal pain 2.   Cramping or bloating 3.   Changes in how often you are having a bowel movement. 4.   Diarrhea 5.   Constipation 6.   Food intolerance 7.   Fatigue and difficulty sleepy   Types of IBS:   1.   IBS-D 2.   IBS-C 3.   IBS-M   Causes of Irritable bowel syndrome:   IBS can develop after a severe attack of diarrhea caused by bacteria or a virus.IBS might also be associated with a surplus of bacteria in the intestines. People exposed to stressful events, especially in childhood tend to have more symptoms of IBS.   Treatment of Irritable bowel syndrome:   The most common treatment of Irritable bowel syndrome is cognitive behavioral therapy which has been considered to be very effective. This therapy is provided by a trained men

How to impede bedsores on a bedridden patient?

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  Bedsores occur when a person is on bed rest or immobile, unconscious or unable to sense pain. Bedsores are basically are ulcers that are formed on the skin that is under pressure for long time .Bedsores are also called pressure injuries ,pressure ulcers. Bedsores is a common problem among older people  and bedsores are related to the quality of care of that person which is bedridden. If a person is unable to sense pain and is not getting good nutrition bedsores can develop. Higher risk of bedsores are among diabetes patient. Bedsores can be cured but need some care. The precaution which have to follow are given below; 1.   We have to remove pressure on affected area. 2.   Protecting the wound with antiseptic gauze or other dressings. 3.   We have to give full good nutrition to patient. 4.   We have to keep the wound clean otherwise bacteria will grow. 5.   Remove all the dead skin around the wound. 6.   Negative pressure wound therapy. 7.   Medicine like cream should

What is the Pros and Cons of a liver transplant?

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  A liver transplant is a wonderful thing when it goes perfectly .This valuable organ is so essential that to get a second liver is extraordinary thing in itself. Another magnificent thing about a liver transplant which you don’t know is that if you are lucky you get a living organ donation what this mean is you have a family member or donor give you roughly 60 percent of their liver because the liver is the fast developing organ. Liver transplants are good because in many of the cases this transplant could add many years to a person’s life. Pros: Most operative treatment for severe liver failure. Have high subsistence rate. A donor have a normal life even after a organ transplant. Cons: Have insufficiency of donors Abridged clotting factors Immunosuppressant’s increase risk of infection in many patients. Denunciation On average, most people who obtain liver transplant live for more than 10 years. Some people may live for up to 10 to 20 years or more after the transplant. A study says

Why heart attack is increasing among the young people?

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  It was rare for anyone younger than 40 to have a heart attack .Now 1 in 5 heart attack patients are younger than 40 years of age.Having a heart attack in your 20s or early . The rise in heart attack among younger people can largely be attributed to lifestyle .Overbooked schudele, pressure to compete ,constant stress and anxiety, overeating and self –medicating with alcohol and drugs take a toll on the heart. Hypertension or high blood pressure is one of the biggest trend factors for cardiovascular disease .inappropriately just like the trend in heart attacks, the occurrence of hypertension is rising faster in young adults than in older adults. High blood pressure makes your heart muscles thicker, harm your blood vessels and increases your risk of a heart attack.     Without warming,your heart stops due to an electrical disturbance that causes an abnormal heart rhythm.Heaert attacks increase the risks of sudden cardiac arrest,which can cause death without immediate treatment.

Blood stem cell development

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Blood stem cells were the first stem cells to be recognized. Their discovery manifest the formation of stem cell research.Today, researchers stay to learn from blood stem cells and are working to recognize new ways to use them in the clinic.   How the blood system is formed is an continuing fundamental research challenge. Developmental biology has provided many insights into molecules and processes that affect the formation of the blood tissues, both in health and disease. It is particular interest for clinical replacement therapies to understand how hematopoietic stem cells of the adult blood system that produe over 10 different functionally specialized cell lineages and over 10 cells daily are produced during embryonic  stages.   The red bone marrow is imitative from the layer of the embryo called the mesoderm.Haematopoiesis is the process by which all mature blood cells are produced .Hematopoietic stem cells give rise to different types of blood cells, in lines called

What are the side effects of using broiler chicken for female?

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    Broiler chicken contains undesirable fats that are harmful to a healthy person. Broiler chicken use can cause problems such as body weight, hypertension, and heart problems. Stop eating highly cooked chickens and choose healthy chicken meat.   Hormonal changes:     Typically, broilers are given growth hormones to help them gain weight faster. There is a concern that when these hormones are consumed, the hormones and antibiotics injected in the broiler may also enter your bodies and cause a health problem.    Breast  cancer:   In women it cause breast cancer and this is getting disturbing common in bodybuilders and fitness curiosities who consume chicken in very high quantities. Some research displays that eating broiler chicken cooked at high temperatures can lead to health complications. In men, ovens can cause prostate cancer disease. Be careful with this and do not cook the chicken meat over high heat. Grilled chickens are cooked at a high temperature and